Frmd3 | FERM domain containing 3

GeneMGI:2442466Synonyms: P410, 9430066I12Rik, +2 more

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Hearing/vestibular/ear Vision/eye Hematopoietic system Behavior/neurological

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased exploration in new environment1 supporting datasetFrmd3em1(IMPC)JhomozygoteEarly adult1.86x10-7 
abnormal auditory brainstem response1 supporting datasetFrmd3em1(IMPC)JhomozygoteEarly adult4.23x10-5 
increased vertical activity1 supporting datasetFrmd3em1(IMPC)JhomozygoteEarly adult7.24x10-5 
decreased leukocyte cell number1 supporting datasetFrmd3em1(IMPC)JhomozygoteEarly adult1.6x10-5 
abnormal cornea morphology1 supporting datasetFrmd3em1(IMPC)JhomozygoteEarly adult1.76x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Frmd3em1(IMPC)JExon Deletionmouse
Frmd3tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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