Unk | unkempt family zinc finger

GeneMGI:2442456Synonyms: Zc3h5, B230379M23Rik

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Mortality/aging

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased erythrocyte cell number	1 supporting dataset	Unk^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.76x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Unk^{tm1a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased grip strength	1 supporting dataset	Unk^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.93x10^-6
increased bone mineral content	1 supporting dataset	Unk^{tm1a(KOMP)Wtsi}	homozygote	Early adult	3.29x10^-6
decreased mean corpuscular hemoglobin	2 supporting datasets	Unk^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.07x10^-8
decreased body length	1 supporting dataset	Unk^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.95x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Unk.

Associated images

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Histopathology

There is no histopathology data found for Unk.

IMPC related publications

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External links

No external links available for Unk.

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*Unk^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Unk^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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