Dusp4 | dual specificity phosphatase 4

GeneMGI:2442191Synonyms: MKP2, E130306H24Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

19 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



decreased circulating glucose level	1 supporting dataset	Dusp4^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.93x10^-7
decreased circulating potassium level	1 supporting dataset	Dusp4^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.13x10^-8
decreased circulating chloride level	1 supporting dataset	Dusp4^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.73x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dusp4.

Associated images

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Histopathology

There is no histopathology data found for Dusp4.

IMPC related publications

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External links

No external links available for Dusp4.

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*Dusp4^em1(IMPC)Bay*	Point Mutation	‌	mouse
*Dusp4^{tm1(EGFP/cre/ERT2)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell mouse
*Dusp4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Dusp4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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