Zc3h12b | zinc finger CCCH-type containing 12B

GeneMGI:2442133Synonyms: LOC245523, A130028J20Rik

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Vision/eye Hematopoietic system Behavior/neurological

12 No significant impact

6 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

small uterus1 supporting datasetZc3h12bem1(IMPC)TcphomozygoteEarly adultN/A * 
microphthalmia1 supporting datasetZc3h12bem1(IMPC)TcphomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetZc3h12bem1(IMPC)TcphomozygoteEarly adultN/A * 
increased mean corpuscular hemoglobin concentration1 supporting datasetZc3h12bem1(IMPC)TcphomozygoteEarly adult1.96x10-6 
abnormal ovary morphology1 supporting datasetZc3h12bem1(IMPC)TcphomozygoteEarly adultN/A * 
impaired cued conditioning behavior1 supporting datasetZc3h12bem1(IMPC)TcphemizygoteEarly adult8.97x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zc3h12bem1(IMPC)TcpExon Deletionmouse
Zc3h12btm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Zc3h12btm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Zc3h12btm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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