Hrh4 | histamine receptor H4

GeneMGI:2429635Synonyms: H4R

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Cardiovascular system

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased cornea thickness	1 supporting dataset	Hrh4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.88x10^-6
decreased total retina thickness	1 supporting dataset	Hrh4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.73x10^-5
decreased heart weight	1 supporting dataset	Hrh4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.07x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hrh4.

Associated images

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Histopathology

There is no histopathology data found for Hrh4.

IMPC related publications

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External links

No external links available for Hrh4.

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*Hrh4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Hrh4^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Hrh4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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