Brms1 | breast cancer metastasis-suppressor 1

GeneMGI:2388804

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased startle reflex	1 supporting dataset	Brms1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	7.37x10^-6
increased circulating chloride level	1 supporting dataset	Brms1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2.54x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Brms1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased circulating sodium level	1 supporting dataset	Brms1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.25x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Brms1.

Associated images

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Histopathology

There is no histopathology data found for Brms1.

IMPC related publications

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External links

No external links available for Brms1.

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*Brms1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Brms1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Brms1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Brms1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Brms1^{tm3(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell

My Genes