Katnal1 | katanin p60 subunit A-like 1

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system Mortality/aging Renal/urinary system

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



increased mean corpuscular hemoglobin concentration	1 supporting dataset	Katnal1^em1(IMPC)Tcp	heterozygote	Early adult	1.09x10^-5
abnormal retina blood vessel morphology	1 supporting dataset	Katnal1^em1(IMPC)Tcp	heterozygote	Early adult	3.74x10^-5
pallor	1 supporting dataset	Katnal1^em1(IMPC)Tcp	homozygote	E18.5	N/A ^*
decreased mean corpuscular volume	1 supporting dataset	Katnal1^em1(IMPC)Tcp	heterozygote	Early adult	3.83x10^-10
abnormal retina vasculature morphology	1 supporting dataset	Katnal1^em1(IMPC)Tcp	heterozygote	Early adult	3.56x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Katnal1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Katnal1^em1(IMPC)Tcp	heterozygote	Early adult	6.69x10^-7
preweaning lethality, incomplete penetrance	2 supporting datasets	Katnal1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged urinary bladder	1 supporting dataset	Katnal1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Katnal1^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Katnal1.

Associated images

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Histopathology

There is no histopathology data found for Katnal1.

IMPC related publications

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External links

No external links available for Katnal1.

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*Katnal1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Katnal1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Katnal1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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