Zfp280c | zinc finger protein 280C

GeneMGI:2387585Synonyms: Zfp633, Suhw3

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological Cardiovascular system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina blood vessel morphology1 supporting datasetZfp280cem1(IMPC)HmguhemizygoteEarly adult1.37x10-12 
abnormal retina blood vessel morphology1 supporting datasetZfp280cem1(IMPC)HmguhomozygoteEarly adult4.84x10-12 
abnormal vitreous body morphology1 supporting datasetZfp280cem1(IMPC)HmguhemizygoteEarly adult7.97x10-8 
abnormal retina morphology1 supporting datasetZfp280cem1(IMPC)HmguhemizygoteEarly adult7.8x10-20 
abnormal retina morphology1 supporting datasetZfp280cem1(IMPC)HmguhomozygoteEarly adult2.92x10-6 
abnormal locomotor behavior1 supporting datasetZfp280cem1(IMPC)HmguhomozygoteEarly adult3.96x10-6 
increased exploration in new environment1 supporting datasetZfp280cem1(IMPC)HmguhomozygoteEarly adult6.74x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfp280cem1(IMPC)HmguExon Deletionmouse
Zfp280ctm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell

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