Ppp1r9b | protein phosphatase 1, regulatory subunit 9B
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological Skeleton
15 No significant impact
6 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
52Embryo tissues
| hyperactivity | 7 supporting datasets | Ppp1r9btm1.1(KOMP)Vlcg | homozygote | Early adult | 2.13x10-15 | ||
| abnormal sleep behavior | 5 supporting datasets | Ppp1r9btm1.1(KOMP)Vlcg | homozygote | Early adult | 1.73x10-12 | ||
| increased exploration in new environment | 1 supporting dataset | Ppp1r9btm1.1(KOMP)Vlcg | homozygote | Early adult | 2.06x10-5 | ||
| increased coping response | 1 supporting dataset | Ppp1r9btm1.1(KOMP)Vlcg | homozygote | Early adult | 2.44x10-5 | ||
| increased circulating aspartate transaminase level | 1 supporting dataset | Ppp1r9btm1.1(KOMP)Vlcg | homozygote | Early adult | 5.36x10-5 | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Ppp1r9btm1.1(KOMP)Vlcg | homozygote | Early adult | 7.88x10-6 | ||
| increased vertical activity | 1 supporting dataset | Ppp1r9btm1.1(KOMP)Vlcg | homozygote | Early adult | 1.86x10-5 | ||
| abnormal bone structure | 1 supporting dataset | Ppp1r9btm1.1(KOMP)Vlcg | homozygote | Early adult | 6.73x10-6 |
| | | | | | | | | | |
| adrenal gland | heterozygote | Section images | 100% (2/2) | 0.7% (4/570) |
| aorta | heterozygote | Section images | 100% (2/2) | 0.19% (1/533) |
| brain | heterozygote | Section images | 100% (2/2) | 0.86% (5/579) |
| brainstem | heterozygote | Section images | 100% (2/2) | 0.41% (2/490) |
| brown adipose tissue | heterozygote | Section images | 100% (2/2) | 0% (0/588) |
| cartilage tissue | heterozygote | Section images | 100% (2/2) | 0.22% (1/454) |
| cerebellum | heterozygote | Section images | 100% (2/2) | 0.56% (3/532) |
| cerebral cortex | heterozygote | Section images | 100% (2/2) | 0.41% (2/491) |
| epididymis | heterozygote | Section images | 100% (1/1) | 87.5% (21/24) |
| esophagus | heterozygote | Section images | 100% (2/2) | 1.67% (7/419) |
Human diseases caused by Ppp1r9b mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Ppp1r9b.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Ppp1r9btm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Ppp1r9btm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Ppp1r9btm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Ppp1r9btm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |