Ppp1r9b | protein phosphatase 1, regulatory subunit 9B

GeneMGI:2387581Synonyms: spinophilin, SPL, +2 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Skeleton

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

52Embryo tissues

Phenotypes

Phy. System:



hyperactivity	7 supporting datasets	Ppp1r9b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.13x10^-15
abnormal sleep behavior	5 supporting datasets	Ppp1r9b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.73x10^-12
increased exploration in new environment	1 supporting dataset	Ppp1r9b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.06x10^-5
increased coping response	1 supporting dataset	Ppp1r9b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.44x10^-5
increased circulating aspartate transaminase level	1 supporting dataset	Ppp1r9b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	5.36x10^-5
increased circulating alanine transaminase level	1 supporting dataset	Ppp1r9b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.88x10^-6
increased vertical activity	1 supporting dataset	Ppp1r9b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.86x10^-5
abnormal bone structure	1 supporting dataset	Ppp1r9b^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.73x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ppp1r9b.

Associated images

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Histopathology

There is no histopathology data found for Ppp1r9b.

IMPC related publications

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External links

No external links available for Ppp1r9b.

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*Ppp1r9b^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Ppp1r9b^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Ppp1r9b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ppp1r9b^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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