Pank4 | pantothenate kinase 4

GeneMGI:2387466Synonyms: D030031I12Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Liver/biliary system Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity2 supporting datasetsPank4em1(IMPC)KmpchomozygoteLate adult4.95x10-5 
abnormal liver morphology1 supporting datasetPank4em1(IMPC)KmpchomozygoteLate adultN/A * 
decreased circulating creatinine level1 supporting datasetPank4em1(IMPC)KmpchomozygoteLate adult1.61x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pank4em1(IMPC)KmpcExon Deletionmouse
Pank4tm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Pank4tm404248(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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