C1ql3 | C1q-like 3

GeneMGI:2387350Synonyms: 1110065A22Rik, K100

Physiological systems

14 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system

11 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased leukocyte cell number1 supporting datasetC1ql3em1(IMPC)HhomozygoteEarly adult3.11x10-8 
decreased lymphocyte cell number1 supporting datasetC1ql3em1(IMPC)HhomozygoteEarly adult1.42x10-7 
increased blood urea nitrogen level1 supporting datasetC1ql3em1(IMPC)HhomozygoteEarly adult1.27x10-7 
decreased eosinophil cell number1 supporting datasetC1ql3em1(IMPC)HhomozygoteEarly adult2.13x10-12 
decreased monocyte cell number1 supporting datasetC1ql3em1(IMPC)HhomozygoteEarly adult2.04x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

Human diseases caused by C1ql3 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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C1ql3em1(IMPC)HIndelmouse
C1ql3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell

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