St8sia6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6

GeneMGI:2386797Synonyms: ST8Sia VI, 1700007J08Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Growth/size/body region Vision/eye Hematopoietic system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

cataract1 supporting datasetSt8sia6em1(IMPC)MbphomozygoteEarly adult9.23x10-5 
abnormal spleen morphology1 supporting datasetSt8sia6em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal vitreous body morphology1 supporting datasetSt8sia6em1(IMPC)MbphomozygoteEarly adult7.3x10-5 
enlarged spleen1 supporting datasetSt8sia6em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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St8sia6em1(IMPC)MbpExon Deletionmouse
St8sia6tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
St8sia6tm51097(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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