Nup153 | nucleoporin 153
Physiological systems
18 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Integument Behavior/neurological Mortality/aging Cardiovascular system
14 No significant impact
6 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Nup153em1(IMPC)J | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Nup153em1(IMPC)J | homozygote | E9.5 | N/A * | ||
| decreased heart weight | 1 supporting dataset | Nup153em1(IMPC)J | heterozygote | Early adult | 6.24x10-5 | ||
| abnormal vocalization | 1 supporting dataset | Nup153em1(IMPC)J | heterozygote | Early adult | 2.42x10-10 | ||
| hyperactivity | 1 supporting dataset | Nup153em1(IMPC)J | heterozygote | Early adult | 7.92x10-5 | ||
| absent vibrissae | 1 supporting dataset | Nup153em1(IMPC)J | heterozygote | Early adult | 4.97x10-7 |
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External links
No external links available for Nup153.
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| Nup153em1(IMPC)J | Exon Deletion | | mouse |
| Nup153tm458604(L1L2_GT1_LF2A_LacZ_BetactP_neo) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |