Klhl12 | kelch-like 12

GeneMGI:2385619Synonyms: C3ip1

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Endocrine/exocrine gland Growth/size/body region Vision/eye Skeleton

14 No significant impact

6 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal sternum morphology1 supporting datasetKlhl12em1(IMPC)TcphomozygoteEarly adultN/A * 
persistence of hyaloid vascular system1 supporting datasetKlhl12em1(IMPC)TcphomozygoteLate adult2.86x10-10 
decreased body length1 supporting datasetKlhl12em1(IMPC)TcphomozygoteEarly adult1.92x10-6 
persistence of hyaloid vascular system1 supporting datasetKlhl12em1(IMPC)TcphomozygoteEarly adult2.99x10-8 
small adrenal glands1 supporting datasetKlhl12em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Klhl12em1(IMPC)TcpExon Deletionmouse
Klhl12tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)ES Cell

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