Dlat | dihydrolipoamide S-acetyltransferase

GeneMGI:2385311Synonyms: PDC-E2, 6332404G05Rik

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Nervous system Behavior/neurological Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased prepulse inhibition	6 supporting datasets	Dlat^em1(IMPC)J	heterozygote	Early adult	2.31x10^-172
decreased exploration in new environment	1 supporting dataset	Dlat^em1(IMPC)J	heterozygote	Early adult	2.12x10^-7
preweaning lethality, complete penetrance	1 supporting dataset	Dlat^em1(IMPC)J	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dlat.

Associated images

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Histopathology

There is no histopathology data found for Dlat.

IMPC related publications

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External links

No external links available for Dlat.

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*Dlat^em1(IMPC)J*	Exon Deletion	‌	mouse
*Dlat^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Dlat^{tm39548(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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