Usp1 | ubiquitin specific peptidase 1

GeneMGI:2385198

Physiological systems

15 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Vision/eye Hematopoietic system Craniofacial

10 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal snout morphology	1 supporting dataset	Usp1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.23x10^-11
increased circulating potassium level	1 supporting dataset	Usp1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.23x10^-6
increased mean corpuscular hemoglobin	1 supporting dataset	Usp1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.05x10^-18
increased blood urea nitrogen level	1 supporting dataset	Usp1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.53x10^-5
increased circulating insulin level	1 supporting dataset	Usp1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	9.77x10^-9
increased circulating creatinine level	1 supporting dataset	Usp1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.48x10^-6
abnormal eyelid aperture	1 supporting dataset	Usp1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.96x10^-6
decreased body length	1 supporting dataset	Usp1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.3x10^-12
decreased erythrocyte cell number	1 supporting dataset	Usp1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.96x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Usp1.

Associated images

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Histopathology

There is no histopathology data found for Usp1.

IMPC related publications

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External links

No external links available for Usp1.

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*Usp1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Usp1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Usp1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Usp1^{tm299930(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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