Clcc1 | chloride channel CLIC-like 1

GeneMGI:2385186Synonyms: Mclc

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Embryo Growth/size/body region Hematopoietic system Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

1Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal embryo turning	1 supporting dataset	Clcc1^{tm1b(KOMP)Mbp}	homozygote	E9.5	N/A ^*
abnormal embryo size	1 supporting dataset	Clcc1^{tm1b(KOMP)Mbp}	homozygote	E9.5	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Clcc1^{tm1b(KOMP)Mbp}	homozygote	E12.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Clcc1^{tm1b(KOMP)Mbp}	homozygote	E9.5	N/A ^*
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Clcc1^{tm1b(KOMP)Mbp}	heterozygote	Early adult	2.83x10^-11
preweaning lethality, complete penetrance	1 supporting dataset	Clcc1^{tm1b(KOMP)Mbp}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Clcc1.

Associated images

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Histopathology

There is no histopathology data found for Clcc1.

IMPC related publications

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External links

No external links available for Clcc1.

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*Clcc1^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Clcc1^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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