Lyplal1 | lysophospholipase-like 1

GeneMGI:2385115Synonyms: Q96AVO

Physiological systems

23 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

17 No significant impact

1 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:75Adult tissues
42Embryo tissues

Phenotypes

increased grip strength2 supporting datasetsLyplal1tm1b(KOMP)WtsihomozygoteEarly adult9.35x10-7 
decreased mean corpuscular volume1 supporting datasetLyplal1tm1b(KOMP)WtsihomozygoteEarly adult2.28x10-6 
vertebral fusion1 supporting datasetLyplal1tm1a(KOMP)WtsihomozygoteEarly adult3.92x10-5 
abnormal vocalization1 supporting datasetLyplal1tm1b(KOMP)WtsihomozygoteEarly adult2.99x10-5 
increased circulating alkaline phosphatase level1 supporting datasetLyplal1tm1a(KOMP)WtsihomozygoteEarly adult4.54x10-7 
eye hemorrhage1 supporting datasetLyplal1tm1b(KOMP)WtsihomozygoteEarly adult2.53x10-6 
increased hematocrit1 supporting datasetLyplal1tm1b(KOMP)WtsihomozygoteEarly adult2.32x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lyplal1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Lyplal1tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Lyplal1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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