Ndufs2 | NADH:ubiquinone oxidoreductase core subunit S2

Physiological systems

11 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Embryo Growth/size/body region Mortality/aging

8 No significant impact

13 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance2 supporting datasetsNdufs2em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal embryo size1 supporting datasetNdufs2em1(IMPC)TcpheterozygoteE9.5N/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetNdufs2em1(IMPC)TcphomozygoteE12.5N/A * 
embryonic lethality prior to organogenesis1 supporting datasetNdufs2em1(IMPC)TcphomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ndufs2em1(IMPC)TcpExon Deletionmouse
Ndufs2tm55519(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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