Pex6 | peroxisomal biogenesis factor 6

GeneMGI:2385054Synonyms: D130055I09Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Embryo Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Mortality/aging

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

8Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	3 supporting datasets	Pex6^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Pex6^em1(IMPC)Tcp	homozygote	E15.5	N/A ^*
microphthalmia	1 supporting dataset	Pex6^em1(IMPC)Bay	homozygote	E18.5	N/A ^*
abnormal embryo size	1 supporting dataset	Pex6^em1(IMPC)Bay	homozygote	E18.5	N/A ^*
microphthalmia	1 supporting dataset	Pex6^em1(IMPC)Tcp	homozygote	E15.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Pex6^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal iris morphology	1 supporting dataset	Pex6^em1(IMPC)Tcp	heterozygote	Early adult	3.65x10^-7
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Pex6^em1(IMPC)Tcp	heterozygote	Early adult	2.56x10^-6
impaired pupillary reflex	1 supporting dataset	Pex6^em1(IMPC)Tcp	heterozygote	Early adult	2.07x10^-5
abnormal cornea morphology	1 supporting dataset	Pex6^em1(IMPC)Tcp	heterozygote	Early adult	6.29x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Pex6.

Associated images

Loading...

Histopathology

There is no histopathology data found for Pex6.

IMPC related publications

Loading...

External links

No external links available for Pex6.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Pex6^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Pex6^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Pex6^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Pex6^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pex6^{tm44758(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes