Lemd2 | LEM domain containing 2

GeneMGI:2385045Synonyms: NET25, Lem2

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Immune system Hematopoietic system Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

5Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, incomplete penetrance	2 supporting datasets	Lemd2^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Lemd2^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Lemd2^em1(IMPC)Bay	homozygote	E12.5	N/A ^*
abnormal spleen morphology	1 supporting dataset	Lemd2^em1(IMPC)Bay	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Lemd2.

Associated images

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Histopathology

There is no histopathology data found for Lemd2.

IMPC related publications

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External links

No external links available for Lemd2.

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*Lemd2^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Lemd2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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