Paip1 | polyadenylate binding protein-interacting protein 1

GeneMGI:2384993

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Hematopoietic system

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased mean corpuscular hemoglobin concentration	1 supporting dataset	Paip1^em1(IMPC)Tcp	homozygote	Early adult	2x10^-10
decreased hematocrit	1 supporting dataset	Paip1^em1(IMPC)Tcp	homozygote	Early adult	5.46x10^-6
male infertility	1 supporting dataset	Paip1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Paip1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
thrombocytosis	1 supporting dataset	Paip1^em1(IMPC)Tcp	homozygote	Early adult	1.57x10^-7
decreased circulating serum albumin level	1 supporting dataset	Paip1^em1(IMPC)Tcp	homozygote	Early adult	6.6x10^-5
decreased mean corpuscular volume	1 supporting dataset	Paip1^em1(IMPC)Tcp	homozygote	Early adult	4.87x10^-13
increased red blood cell distribution width	1 supporting dataset	Paip1^em1(IMPC)Tcp	homozygote	Early adult	5.44x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Paip1.

Associated images

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Histopathology

There is no histopathology data found for Paip1.

IMPC related publications

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External links

No external links available for Paip1.

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*Paip1^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Paip1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

My Genes