Dhrs7b | dehydrogenase/reductase 7B

GeneMGI:2384931Synonyms: dehydrogenase/reductase (SDR family) member 7B

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



no spontaneous movement	1 supporting dataset	Dhrs7b^em1(IMPC)Mbp	heterozygote	E18.5	N/A ^*
increased circulating alanine transaminase level	1 supporting dataset	Dhrs7b^em1(IMPC)Mbp	heterozygote	Early adult	2.75x10^-9
no spontaneous movement	1 supporting dataset	Dhrs7b^em1(IMPC)Mbp	homozygote	E18.5	N/A ^*
increased circulating HDL cholesterol level	1 supporting dataset	Dhrs7b^em1(IMPC)Mbp	heterozygote	Early adult	9.03x10^-5
abnormal freezing behavior	1 supporting dataset	Dhrs7b^em1(IMPC)Mbp	heterozygote	Early adult	1.29x10^-5
preweaning lethality, incomplete penetrance	2 supporting datasets	Dhrs7b^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Dhrs7b^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Dhrs7b.

Associated images

Loading...

Histopathology

There is no histopathology data found for Dhrs7b.

IMPC related publications

Loading...

External links

No external links available for Dhrs7b.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Dhrs7b^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Dhrs7b^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Dhrs7b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Dhrs7b^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Dhrs7b^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Dhrs7b^{tm39122(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes