Rhbdl1 | rhomboid like 1
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Mortality/aging
16 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:42Adult tissues
29Embryo tissues
increased circulating alanine transaminase level | 1 supporting dataset | Rhbdl1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 3.48x10-5 | ||
increased circulating aspartate transaminase level | 1 supporting dataset | Rhbdl1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.21x10-5 | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Rhbdl1tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
increased circulating bilirubin level | 1 supporting dataset | Rhbdl1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.38x10-5 | ||
abnormal skin morphology | 1 supporting dataset | Rhbdl1tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
embryonic lethality prior to organogenesis | 1 supporting dataset | Rhbdl1tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * |
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External links
No external links available for Rhbdl1.
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Rhbdl1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
Rhbdl1tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
Rhbdl1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Rhbdl1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |