Prmt7 | protein arginine N-methyltransferase 7

GeneMGI:2384879Synonyms: 4933402B05Rik

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

2Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased lean body mass	1 supporting dataset	Prmt7^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.67x10^-6
decreased hemoglobin content	1 supporting dataset	Prmt7^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.17x10^-9
abnormal behavior	2 supporting datasets	Prmt7^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.29x10^-10
decreased body length	1 supporting dataset	Prmt7^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.28x10^-5
increased total body fat amount	1 supporting dataset	Prmt7^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.27x10^-6
decreased erythrocyte cell number	1 supporting dataset	Prmt7^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.05x10^-10
abnormal rib morphology	1 supporting dataset	Prmt7^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	8.01x10^-8
decreased bone mineral content	1 supporting dataset	Prmt7^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.48x10^-5
decreased hematocrit	1 supporting dataset	Prmt7^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.52x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prmt7.

Associated images

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Histopathology

There is no histopathology data found for Prmt7.

IMPC related publications

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External links

No external links available for Prmt7.

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*Prmt7^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Prmt7^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Prmt7^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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