Cmtr2 | cap methyltransferase 2

GeneMGI:2384580Synonyms: C730036L12Rik, Ftsjd1

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Embryo Growth/size/body region Cardiovascular system Mortality/aging

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



embryonic growth retardation	1 supporting dataset	Cmtr2^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*
increased lean body mass	2 supporting datasets	Cmtr2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	4.08x10^-7
decreased total body fat amount	1 supporting dataset	Cmtr2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	7.08x10^-5
increased heart weight	1 supporting dataset	Cmtr2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	8x10^-9
decreased circulating creatinine level	1 supporting dataset	Cmtr2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2.91x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Cmtr2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal embryo turning	1 supporting dataset	Cmtr2^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cmtr2.

Associated images

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Histopathology

There is no histopathology data found for Cmtr2.

IMPC related publications

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External links

No external links available for Cmtr2.

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*Cmtr2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Cmtr2^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Cmtr2^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Cmtr2^{tm97095(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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