Cbr4 | carbonyl reductase 4

GeneMGI:2384567Synonyms: A730083J17Rik

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Skeleton Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased bone mineral content	2 supporting datasets	Cbr4^em1(IMPC)Bay	heterozygote	Early adult	2.31x10^-6
preweaning lethality, complete penetrance	3 supporting datasets	Cbr4^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
increased bone mineral density	1 supporting dataset	Cbr4^em1(IMPC)Bay	heterozygote	Early adult	2.06x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cbr4.

Associated images

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Histopathology

There is no histopathology data found for Cbr4.

IMPC related publications

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External links

No external links available for Cbr4.

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*Cbr4^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Cbr4^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Cbr4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Cbr4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Cbr4^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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