Polr2h | polymerase (RNA) II (DNA directed) polypeptide H
GeneMGI:2384309
Physiological systems
19 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Mortality/aging
17 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
25Embryo tissues
| increased circulating free fatty acids level | 1 supporting dataset | Polr2htm1.1(KOMP)Wtsi | heterozygote | Early adult | 6.63x10-6 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Polr2htm1.1(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Polr2htm1.1(KOMP)Wtsi | homozygote | E12.5 | N/A * | ||
| decreased circulating sodium level | 1 supporting dataset | Polr2htm1.1(KOMP)Wtsi | heterozygote | Early adult | 2.25x10-6 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Polr2htm1.1(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| decreased circulating iron level | 1 supporting dataset | Polr2htm1.1(KOMP)Wtsi | heterozygote | Early adult | 8x10-9 |
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External links
No external links available for Polr2h.
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| Polr2htm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell mouse |
| Polr2htm1.1(KOMP)Wtsi | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |