Myo3a | myosin IIIA

GeneMGI:2183924Synonyms: 9030416P08Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hearing/vestibular/ear Behavior/neurological

15 No significant impact

6 Not tested

Gene metrics:4Significant phenotypes
3Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues

Phenotypes

decreased thigmotaxis2 supporting datasetsMyo3atm1b(KOMP)WtsihomozygoteEarly adult1.65x10-5 
abnormal auditory brainstem response3 supporting datasetsMyo3atm1b(KOMP)WtsihomozygoteEarly adult1.1x10-12 
hyperactivity1 supporting datasetMyo3atm1b(KOMP)WtsihomozygoteEarly adult9.31x10-7 
impaired glucose tolerance1 supporting datasetMyo3atm1b(KOMP)WtsihomozygoteEarly adult3.54x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Myo3atm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Myo3atm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Myo3atm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Myo3atm266869(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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