Nav2 | neuron navigator 2

GeneMGI:2183691Synonyms: Unc53H2, Rainb1, +4 more

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Integument Hematopoietic system Behavior/neurological Renal/urinary system

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased thigmotaxis	2 supporting datasets	Nav2^em1(IMPC)Tcp	homozygote	Early adult	4.68x10^-5
decreased exploration in new environment	1 supporting dataset	Nav2^em1(IMPC)Tcp	homozygote	Early adult	6.34x10^-8
increased neutrophil cell number	1 supporting dataset	Nav2^em1(IMPC)Tcp	homozygote	Early adult	2.5x10^-5
abnormal skin morphology	1 supporting dataset	Nav2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased circulating aspartate transaminase level	1 supporting dataset	Nav2^em1(IMPC)Tcp	homozygote	Early adult	1.37x10^-7
small kidney	1 supporting dataset	Nav2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
hyperactivity	4 supporting datasets	Nav2^em1(IMPC)Tcp	homozygote	Early adult	6.89x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nav2.

Associated images

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Histopathology

There is no histopathology data found for Nav2.

IMPC related publications

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External links

No external links available for Nav2.

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*Nav2^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Nav2^{tm457487(L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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