Nav1 | neuron navigator 1

GeneMGI:2183683Synonyms: POMFIL3, C230080M11Rik, +3 more

Physiological systems

19 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Nervous system Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

11 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased grip strength	1 supporting dataset	Nav1^em1(IMPC)Mbp	homozygote	Early adult	7.27x10^-5
abnormal kidney morphology	1 supporting dataset	Nav1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Nav1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
prolonged RR interval	1 supporting dataset	Nav1^em1(IMPC)Mbp	homozygote	Early adult	6.21x10^-9
increased freezing behavior	1 supporting dataset	Nav1^em1(IMPC)Mbp	homozygote	Early adult	1.51x10^-7
abnormal spleen morphology	1 supporting dataset	Nav1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
hyperactivity	4 supporting datasets	Nav1^em1(IMPC)Mbp	homozygote	Early adult	7.9x10^-6
abnormal brain morphology	1 supporting dataset	Nav1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased brain size	1 supporting dataset	Nav1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Nav1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Nav1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Nav1.

IMPC related publications

Loading...

External links

No external links available for Nav1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Nav1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Nav1^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Nav1^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

My Genes