Rab40c | Rab40C, member RAS oncogene family

GeneMGI:2183454Synonyms: RAR3

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Mortality/aging

16 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance1 supporting datasetRab40ctm1b(KOMP)WtsihomozygoteEarly adultN/A * 
decreased mean corpuscular hemoglobin1 supporting datasetRab40ctm1b(KOMP)WtsiheterozygoteEarly adult1.86x10-6 
increased circulating sodium level1 supporting datasetRab40ctm1b(KOMP)WtsiheterozygoteEarly adult1.75x10-10 
prenatal lethality1 supporting datasetRab40ctm1b(KOMP)WtsihomozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rab40ctm119149(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Rab40ctm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Rab40ctm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Rab40ctm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Rab40ctm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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