Irak4 | interleukin-1 receptor-associated kinase 4

GeneMGI:2182474Synonyms: IRAK-4, 8430405M07Rik, +2 more

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Hematopoietic system Cardiovascular system

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged thymus	1 supporting dataset	Irak4^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal skin morphology	2 supporting datasets	Irak4^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
thick ventricular wall	1 supporting dataset	Irak4^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.51x10^-5
abnormal seminal vesicle morphology	1 supporting dataset	Irak4^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Irak4^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Irak4.

Associated images

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Histopathology

There is no histopathology data found for Irak4.

IMPC related publications

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External links

No external links available for Irak4.

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*Irak4^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Irak4^{tm40118(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes