Ropn1l | ropporin 1-like

GeneMGI:2182357Synonyms: AKAP-associated sperm protein, ASP

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Growth/size/body region Behavior/neurological Skeleton Craniofacial

14 No significant impact

6 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

abnormal spine curvature1 supporting datasetRopn1ltm1b(EUCOMM)WtsihomozygoteEarly adult5.04x10-5 
kyphosis1 supporting datasetRopn1ltm1b(EUCOMM)WtsihomozygoteEarly adult7.53x10-6 
abnormal tooth morphology1 supporting datasetRopn1ltm1b(EUCOMM)WtsihomozygoteEarly adult9.12x10-5 
decreased grip strength1 supporting datasetRopn1ltm1b(EUCOMM)WtsihomozygoteEarly adult7.85x10-5 
abnormal snout morphology1 supporting datasetRopn1ltm1b(EUCOMM)WtsihomozygoteEarly adult5.59x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ropn1ltm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ropn1ltm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Ropn1ltm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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