Odf4 | outer dense fiber of sperm tails 4
Physiological systems
21 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Reproductive system Growth/size/body region Cardiovascular system Renal/urinary system
17 No significant impact
3 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
| male infertility | 1 supporting dataset | Odf4tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| enlarged heart | 1 supporting dataset | Odf4tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| abnormal urinary bladder morphology | 1 supporting dataset | Odf4tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * |
| | | | | | | | | | |
| adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
| aorta | heterozygote | n/a | 0% (0/1) | 0.19% (1/533) |
| blood | heterozygote | n/a | 0% (0/2) | 0% (0/17) |
| bone marrow | heterozygote | n/a | 0% (0/2) | 0% (0/22) |
| brain | heterozygote | n/a | 0% (0/2) | 0.86% (5/579) |
| brainstem | heterozygote | n/a | n/a | 0.41% (2/490) |
| brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
| cartilage tissue | heterozygote | n/a | n/a | 0.22% (1/454) |
| cecum | heterozygote | n/a | 0% (0/2) | 7.75% (22/284) |
| cerebellum | heterozygote | n/a | 0% (0/2) | 0.56% (3/532) |
Human diseases caused by Odf4 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Odf4.
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| Odf4tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Odf4tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Odf4tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Odf4tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |