Bbc3 | BCL2 binding component 3

GeneMGI:2181667Synonyms: PUMA

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Hematopoietic system Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased mean corpuscular hemoglobin concentration	1 supporting dataset	Bbc3^{em1(IMPC)Marc}	homozygote	Early adult	1.7x10^-16
hyperactivity	4 supporting datasets	Bbc3^{em1(IMPC)Marc}	homozygote	Early adult	3.46x10^-6
increased mean corpuscular hemoglobin	1 supporting dataset	Bbc3^{em1(IMPC)Marc}	homozygote	Early adult	2.41x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bbc3.

Associated images

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Histopathology

There is no histopathology data found for Bbc3.

IMPC related publications

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External links

No external links available for Bbc3.

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*Bbc3^{em1(IMPC)Marc}*	Deletion	‌	mouse
*Bbc3^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Bbc3^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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