Nup155 | nucleoporin 155
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Mortality/aging
16 No significant impact
3 Not tested
Data collections
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged lymph nodes | 1 supporting dataset | Nup155em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal lymph node morphology | 1 supporting dataset | Nup155em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| enlarged spleen | 1 supporting dataset | Nup155em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Nup155em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Nup155em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Nup155em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| increased blood urea nitrogen level | 1 supporting dataset | Nup155em1(IMPC)Mbp | heterozygote | Early adult | 8.37x10-5 |
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Human diseases caused by Nup155 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Nup155.
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| Nup155em1(IMPC)Mbp | Exon Deletion | | mouse |
| Nup155tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Nup155tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |