Mkrn3 | makorin, ring finger protein, 3

GeneMGI:2181178Synonyms: D7H15S9-1, Zfp127

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Homeostasis/metabolism

16 No significant impact

7 Not tested

Gene metrics:1Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased fasting circulating glucose level1 supporting datasetMkrn3em1(IMPC)TcphomozygoteEarly adult2.15x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Human diseases caused by Mkrn3 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

IMPC related publications

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Mkrn3em1(IMPC)TcpIntra-exon deletionmouse
Mkrn3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell

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