Rttn | rotatin

GeneMGI:2179288Synonyms: C530033I08Rik, 4921538A15Rik

Physiological systems

21 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Immune system Integument Embryo Growth/size/body region Digestive/alimentary Liver/biliary system Hematopoietic system Skeleton Mortality/aging Cardiovascular system Renal/urinary system

10 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal skin morphology	1 supporting dataset	Rttn^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Rttn^em1(IMPC)Tcp	heterozygote	Late adult	N/A ^*
prenatal lethality prior to heart atrial septation	1 supporting dataset	Rttn^em1(IMPC)Tcp	homozygote	E15.5	N/A ^*
abnormal embryo size	1 supporting dataset	Rttn^em1(IMPC)Tcp	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Rttn^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Rttn^em1(IMPC)Tcp	homozygote	E9.5	N/A ^*
enlarged urinary bladder	1 supporting dataset	Rttn^em1(IMPC)Tcp	heterozygote	Late adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Rttn^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
decreased bone mineral content	1 supporting dataset	Rttn^em1(IMPC)Tcp	heterozygote	Late adult	1.49x10^-5
small heart	1 supporting dataset	Rttn^em1(IMPC)Tcp	heterozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rttn.

Associated images

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Histopathology

There is no histopathology data found for Rttn.

IMPC related publications

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External links

No external links available for Rttn.

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*Rttn^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Rttn^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rttn^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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