Plxna4 | plexin A4

GeneMGI:2179061Synonyms: Plxa4

Physiological systems

20 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Nervous system Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological

10 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal testis morphology	1 supporting dataset	Plxna4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Plxna4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
persistence of hyaloid vascular system	1 supporting dataset	Plxna4^em1(IMPC)Mbp	homozygote	Early adult	1.6x10^-5
increased exploration in new environment	1 supporting dataset	Plxna4^em1(IMPC)Mbp	homozygote	Early adult	1.07x10^-5
abnormal vitreous body morphology	1 supporting dataset	Plxna4^em1(IMPC)Mbp	homozygote	Early adult	7.3x10^-5
decreased body length	1 supporting dataset	Plxna4^em1(IMPC)Mbp	homozygote	Early adult	2.78x10^-5
small spleen	1 supporting dataset	Plxna4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
hyperactivity	3 supporting datasets	Plxna4^em1(IMPC)Mbp	homozygote	Early adult	1.15x10^-8
abnormal optic disk morphology	1 supporting dataset	Plxna4^em1(IMPC)Mbp	homozygote	Early adult	9.07x10^-5
cataract	1 supporting dataset	Plxna4^em1(IMPC)Mbp	homozygote	Early adult	9.23x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Plxna4.

Associated images

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Histopathology

There is no histopathology data found for Plxna4.

IMPC related publications

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External links

No external links available for Plxna4.

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*Plxna4^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Plxna4^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Plxna4^{tm37345(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Plxna4^{tm37345(L1L2_st0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Plxna4^{tm40385(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Plxna4^{tm40385(L1L2_st0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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