Akap9 | A kinase anchor protein 9

GeneMGI:2178217Synonyms: G1-448-15, 5730481H23Rik, +3 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Skeleton Mortality/aging

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

3Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased bone mineral content	1 supporting dataset	Akap9^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	5x10^-10
decreased total body fat amount	1 supporting dataset	Akap9^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	1.2x10^-6
decreased body weight	2 supporting datasets	Akap9^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	2.66x10^-6
decreased circulating serum albumin level	1 supporting dataset	Akap9^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	5.75x10^-8
abnormal head morphology	1 supporting dataset	Akap9^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	4.34x10^-7
increased circulating alkaline phosphatase level	1 supporting dataset	Akap9^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	2.39x10^-23
decreased circulating LDL cholesterol level	1 supporting dataset	Akap9^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	1.44x10^-10
increased lean body mass	1 supporting dataset	Akap9^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	4.15x10^-9
increased circulating amylase level	1 supporting dataset	Akap9^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	1.78x10^-5
decreased circulating HDL cholesterol level	1 supporting dataset	Akap9^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	2.52x10^-12

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Akap9.

Associated images

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Histopathology

There is no histopathology data found for Akap9.

IMPC related publications

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External links

No external links available for Akap9.

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*Akap9^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Akap9^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Akap9^{tm292971(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Akap9^{tm37213(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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