Helq | helicase, POLQ-like
Physiological systems
20 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Reproductive system Endocrine/exocrine gland Adipose tissue Growth/size/body region Limbs/digits/tail Vision/eye Skeleton Renal/urinary system
12 No significant impact
4 Not tested
Data collections
Gene metrics:13Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased total body fat amount | 2 supporting datasets | Helqem1(IMPC)Mbp | homozygote | Early adult | 1.07x10-10 | ||
| abnormal caudal vertebrae morphology | 1 supporting dataset | Helqem1(IMPC)Mbp | homozygote | Early adult | 1.19x10-6 | ||
| small testis | 1 supporting dataset | Helqem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| female infertility | 1 supporting dataset | Helqem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal kidney morphology | 1 supporting dataset | Helqem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| decreased lean body mass | 2 supporting datasets | Helqem1(IMPC)Mbp | homozygote | Early adult | 1.54x10-10 | ||
| decreased bone mineral content | 1 supporting dataset | Helqem1(IMPC)Mbp | homozygote | Early adult | 7.21x10-10 | ||
| abnormal testis morphology | 1 supporting dataset | Helqem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| small kidney | 1 supporting dataset | Helqem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| male infertility | 1 supporting dataset | Helqem1(IMPC)Mbp | homozygote | Early adult | N/A * |
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External links
No external links available for Helq.
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| Helqem1(IMPC)Mbp | Exon Deletion | | mouse |
| Helqtm44631(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |