Usp33 | ubiquitin specific peptidase 33

GeneMGI:2159711Synonyms: 9830169D19Rik, Vdu1

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Hematopoietic system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



thrombocytosis	1 supporting dataset	Usp33^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.49x10^-5
increased circulating cholesterol level	1 supporting dataset	Usp33^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.36x10^-7
increased circulating LDL cholesterol level	1 supporting dataset	Usp33^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.66x10^-9
increased circulating alanine transaminase level	1 supporting dataset	Usp33^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.5x10^-9
decreased body weight	3 supporting datasets	Usp33^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.12x10^-5
increased circulating bilirubin level	1 supporting dataset	Usp33^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.84x10^-5
increased circulating HDL cholesterol level	1 supporting dataset	Usp33^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.14x10^-7
increased circulating aspartate transaminase level	1 supporting dataset	Usp33^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.16x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Usp33.

Associated images

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Histopathology

There is no histopathology data found for Usp33.

IMPC related publications

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External links

No external links available for Usp33.

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*Usp33^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Usp33^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Usp33^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Usp33^{tm45697(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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