Vangl1 | VANGL planar cell polarity 1

GeneMGI:2159344Synonyms: Lpp2, stbm, +2 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

3Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased mean corpuscular hemoglobin	1 supporting dataset	Vangl1^{tm1e(KOMP)Wtsi}	heterozygote	Early adult	7.56x10^-5
increased circulating aspartate transaminase level	1 supporting dataset	Vangl1^{tm1e(KOMP)Wtsi}	heterozygote	Early adult	8.34x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Vangl1^{tm1e(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
thrombocytosis	1 supporting dataset	Vangl1^{tm1e(KOMP)Wtsi}	heterozygote	Early adult	9.9x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Vangl1.

Associated images

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Histopathology

There is no histopathology data found for Vangl1.

IMPC related publications

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External links

No external links available for Vangl1.

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*Vangl1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Vangl1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell mouse
*Vangl1^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Vangl1^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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