Med16 | mediator complex subunit 16
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Embryo Growth/size/body region Liver/biliary system Mortality/aging
15 No significant impact
5 Not tested
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues
| abnormal placenta size | 1 supporting dataset | Med16tm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Med16tm1b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| pale yolk sac | 1 supporting dataset | Med16tm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * | ||
| preweaning lethality, complete penetrance | 2 supporting datasets | Med16tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Med16tm1b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| abnormal placenta size | 1 supporting dataset | Med16tm1b(KOMP)Wtsi | heterozygote | E12.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Med16tm1b(KOMP)Wtsi | heterozygote | E12.5 | N/A * | ||
| pale liver | 1 supporting dataset | Med16tm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Med16tm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * |
| | | | | | | | | | |
External links
No external links available for Med16.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Med16tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Med16tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Med16tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |