Rln3 | relaxin 3

GeneMGI:2158015Synonyms: M3

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Integument Adipose tissue Hematopoietic system Skeleton

11 No significant impact

7 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:152Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/hair pigmentation3 supporting datasetsRln3tm1(KOMP)MbphomozygoteEarly adult1.21x10-11 
increased circulating iron level1 supporting datasetRln3tm1(KOMP)MbphomozygoteEarly adult8.81x10-6 
decreased bone mineral content1 supporting datasetRln3tm1(KOMP)MbphomozygoteEarly adult5.58x10-6 
decreased hemoglobin content1 supporting datasetRln3tm1(KOMP)MbphomozygoteEarly adult3.71x10-6 
increased total body fat amount1 supporting datasetRln3tm1(KOMP)MbphomozygoteEarly adult3.52x10-6 
decreased erythrocyte cell number1 supporting datasetRln3tm1(KOMP)MbphomozygoteEarly adult1.8x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rln3tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
mouse

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