Phf5a | PHD finger protein 5A

GeneMGI:2156864Synonyms: 1110007B08Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Hematopoietic system Skeleton

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased bone mineral content	2 supporting datasets	Phf5a^{em2(IMPC)Marc}	heterozygote	Early adult	1.46x10^-14
decreased erythrocyte cell number	1 supporting dataset	Phf5a^{em2(IMPC)Marc}	heterozygote	Early adult	9.92x10^-7
increased red blood cell distribution width	1 supporting dataset	Phf5a^{em2(IMPC)Marc}	heterozygote	Early adult	3.31x10^-5
decreased total body fat amount	1 supporting dataset	Phf5a^{em2(IMPC)Marc}	heterozygote	Early adult	6.23x10^-8
increased mean corpuscular volume	1 supporting dataset	Phf5a^{em2(IMPC)Marc}	heterozygote	Early adult	2.74x10^-15
increased fasting circulating glucose level	1 supporting dataset	Phf5a^{em2(IMPC)Marc}	heterozygote	Early adult	5.8x10^-9
increased mean platelet volume	1 supporting dataset	Phf5a^{em2(IMPC)Marc}	heterozygote	Early adult	5x10^-15
increased lean body mass	1 supporting dataset	Phf5a^{em2(IMPC)Marc}	heterozygote	Early adult	5.55x10^-7
abnormal bone structure	1 supporting dataset	Phf5a^{em2(IMPC)Marc}	heterozygote	Early adult	2.85x10^-6
increased mean corpuscular hemoglobin	1 supporting dataset	Phf5a^{em2(IMPC)Marc}	heterozygote	Early adult	4.55x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Phf5a.

Associated images

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Histopathology

There is no histopathology data found for Phf5a.

IMPC related publications

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External links

No external links available for Phf5a.

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*Phf5a^{em2(IMPC)Marc}*	Deletion	‌	mouse
*Phf5a^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Phf5a^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Phf5a^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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