P2ry14 | purinergic receptor P2Y, G-protein coupled, 14

GeneMGI:2155705Synonyms: Gpr105, A330108O13Rik, +1 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Limbs/digits/tail Skeleton

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

long tibia1 supporting datasetP2ry14em1(IMPC)HhomozygoteEarly adult2.94x10-6 
increased total body fat amount2 supporting datasetsP2ry14em1(IMPC)HhomozygoteEarly adult1.5x10-7 
increased circulating alanine transaminase level1 supporting datasetP2ry14em1(IMPC)HhomozygoteLate adult4.13x10-16 
decreased fasting circulating glucose level1 supporting datasetP2ry14em1(IMPC)HhomozygoteLate adult5.36x10-6 
increased circulating aspartate transaminase level1 supporting datasetP2ry14em1(IMPC)HhomozygoteLate adult9.12x10-14 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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P2ry14em1(IMPC)HExon Deletionmouse
P2ry14em2(IMPC)HExon Deletionmouse

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