Plxnb2 | plexin B2

GeneMGI:2154239Synonyms: 1110007H23Rik, Debt

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Growth/size/body region Hematopoietic system Behavior/neurological Renal/urinary system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased IgE level1 supporting datasetPlxnb2tm1a(EUCOMM)WtsiheterozygoteEarly adult3.92x10-6 
abnormal response to tactile stimuli1 supporting datasetPlxnb2tm1a(EUCOMM)WtsiheterozygoteEarly adult6.38x10-6 
abnormal urination1 supporting datasetPlxnb2tm1a(EUCOMM)WtsiheterozygoteEarly adult8.57x10-6 
increased lean body mass1 supporting datasetPlxnb2tm1a(EUCOMM)WtsiheterozygoteEarly adult9.53x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Plxnb2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Plxnb2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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