Trrap | transformation/transcription domain-associated protein

GeneMGI:2153272Synonyms: transactivation/transformation-domain associated protein

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological Mortality/aging

15 No significant impact

4 Not tested

Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

increased mean corpuscular hemoglobin1 supporting datasetTrraptm1a(EUCOMM)WtsiheterozygoteEarly adult6.99x10-8 
abnormal behavior1 supporting datasetTrraptm1a(EUCOMM)WtsiheterozygoteEarly adult8.41x10-5 
abnormal cornea morphology1 supporting datasetTrraptm1a(EUCOMM)WtsiheterozygoteEarly adult9.85x10-5 
preweaning lethality, complete penetrance1 supporting datasetTrraptm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased mean corpuscular volume1 supporting datasetTrraptm1a(EUCOMM)WtsiheterozygoteEarly adult7.36x10-5 
increased circulating magnesium level1 supporting datasetTrraptm1a(EUCOMM)WtsiheterozygoteEarly adult4.63x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Trraptm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Trraptm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Trraptm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Trraptm39907(pL1L2_GT2_DelLacZ_bsd)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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